Product Name：MxSafe（Security nucleic acid dye）

Catalog Number: Mx007

HeLa cells were incubated at 37 ^oC with 1X of SYBR Green I, MxSafe and MxSafe Plus,respectively. Images were taken 

following incubation for 5 min (panel A) and 30 min (panel B), respectively.SYBR Green I entered into cells rapidly as ev

-ident from the bright green nuclear staining. However, MxSafe and MxSafe Plus were unable to cross cell membranes 

as shown by the lack of any fluorescence staining.

MxSafe  is an ultra sensitive, extremely stable and environmentally safe fluorescent nucleic acid dye designed to replace 

the highly toxic ethidium bromide (EB) for staining dsDNA, ssDNA or RNA in agarose gels or polyacrylamide gels. MxSafe 

is far more sensitivethan EB without requiring a destaining step. MxSafe and EB have virtually the same spectra, so you 

can directly replace EB with MxSafe  without changing your existing imaging system.

MxSafe is a very stable dye. Store 10,000X solution and dilute solutions of MxSafe  at room temperature, protected 

from light. Dye  precipitation  may  occur  at  lower  temperatures, resulting  in lower  signal  or  the  appearance  of 

precipitate on the surface of the gel. If this occurs, heat the solution to 45-50^oC for two minutes and vortex. 

MxSafeis stable for at least 3 year from the date it is received.